Barely Significant
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A SELEX-screened aptamer of human hepatitis B virus RNA encapsidation signal suppresses viral replication.

PLoS One · 2011 · PMC3220704 · PMID 22125633

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may not be significantno p-value reported
Given the difficulties in accurately quantitating the broadly distributed signals the latter reduction may not be significant; clearly, however, the data indicated a dose-dependent, specific inhibition of the formation of authentic wild-type ε RNA - miniP complexes.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.