Paradoxical ventilator associated pneumonia incidences among selective digestive decontamination studies versus other studies of mechanically ventilated patients: benchmarking the evidence base.

Systematic reviews of more than 30 controlled studies of SDD provide compelling evidence of reductions in VAP of >50% [ 6 ] versus marginally significant reductions of <20% with non-antibiotic methods of prevention such as those based on the management of gastric pH [ 7 ], tracheal suction [ 8 ], or humidification [ 9 ].

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