QTL analysis identifies a modifier locus of aganglionosis in the rat model of Hirschsprung disease carrying Ednrb(sl) mutations.

PLoS One · 2011 · PMC3222640 · PMID 22132166

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highly significantno p-value reported

QTL analysis identifies modifiers of aganglionosis severity in Ednrb sl/sl rats Final results of interval mapping were considered suggestive, significant, or highly significant linkages when the threshold likelihood ratio statistics (LRS) were 9.9, 20.2, and 30.4, respectively.

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