concluded that despite significantly shorter cardiopulmonary bypass duration in their cohort, SLT recipients with underlying PH had significantly less functional recovery (less reduction in mean pulmonary artery pressure and increase in cardiac index) and higher graft mortality compared with BLT and HLT recipients.[ 45 ] The Hopkins experience evaluated 15 patients with iPAH and found BLT to have a highly significant survival advantage compared with SLT at 4 years of follow-up.[ 51 ] The most recent ISHLT registry reported 788 iPAH lung transplant recipients of which 91% were BLT, highlighting the continuing trend at most centers favoring BLT versus SLT for iPAH.[ 27 ] Outcomes following heart-lung transplantation for pulmonary hypertension According to the 2009 ISHLT registry report comparing the outcome of HLT with BLT for pulmonary hypertension demonstrated similar survival between the two groups.
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