Caprine prion gene polymorphisms are associated with decreased incidence of classical scrapie in goat herds in the United Kingdom.

Vet Res · 2011 · PMC3224758 · PMID 22040234

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highly significantno p-value reported

The PrP variant encoding lysine in codon 222 (K222) has been associated with highly significant protection from scrapie in Italian and French studies [ 14 , 15 ], whereas the codon 146 serine (S146) and 146 aspartic acid (D146) variants have been similarly associated with scrapie resistance in Cypriot herds [ 16 , 17 ].

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