close to significanceP = 0.09
The difference reached significance for donor 1 ( P = 0.0051), donor 3 ( P = 0.005), and donor 5 ( P = 0.02), and were close to significance for donor 2 ( P = 0.09) and donor 4 ( P = 0.07) using the Mann-Whitney U test ( Fig. 5A ).