Whereas miRNAs did not seem to target the 3′ end of the 3′UTR (2574–3180), the remaining fragments mediated a slight increase in reporter activity upon Dicer knock-down and the 5′ fragment 1–449 nt showed a highly significant effect.
← all excerpts
A systematic analysis of the 3'UTR of HNF4A mRNA reveals an interplay of regulatory elements including miRNA target sites.
1
—
—