Evaluation of the NOD/SCID xenograft model for glucocorticoid-regulated gene expression in childhood B-cell precursor acute lymphoblastic leukemia.

BMC Genomics · 2011 · PMC3228854 · PMID 22093874

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highly significantno p-value reported

In addition, in the cell line study, the GR (NR3C1) undergoes highly significant early and sustained autoupregulation, which in the continuous presence of ligand drives downstream gene expression.

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