Importance of optimal dosing ≥ 30 mg/kg/d during deferasirox treatment: 2.7-yr follow-up from the ESCALATOR study in patients with β-thalassaemia.

Eur J Haematol · 2011 · PMC3229712 · PMID 21668502

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an increasing trendno p-value reported

Doses were increased if serum ferritin levels increased by ≥1000 ng/mL above baseline on two consecutive visits or were >2500 ng/mL (changed to >1000 ng/mL in amendment 4) without a decreasing trend (or >500 ng/mL with an increasing trend, added in amendment 4).

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