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Oxygen/ozone as a medical gas mixture. A critical evaluation of the various methods clarifies positive and negative aspects.

Med Gas Res · 2011 · PMC3231820 · PMID 22146387

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a worrying trendno p-value reported
Owing to the vast number of patients, a worrying trend is the invention of cheap and rapid ozone treatments which are based on approaches which may be either unsafe or ineffective.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.