A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease.

PLoS One · 2011 · PMC3237323 · PMID 22194796

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not quite statistically significantno p-value reported

Figure 7B shows that there is a significant reduction in the amount of Iba-1 in the hippocampus of J147-treated huAPP/PS1 mice relative to control huAPP/PS1 mice while the reduction of iNOS is not quite statistically significant due to the large mouse to mouse variability with this marker ( Fig. 7C ).

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