Isoform specific qRT-PCR indicated a highly significant down-regulation of both individual mRNA splice isoforms and total length Sfrs10 mRNA in neuronal specific Sfrs10 -depleted mice Sfrs10 fl/fl Nestin-Cre tg/+ ) compared to controls at 16.5 dpc ( Figure 8C ).
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Identification of evolutionarily conserved exons as regulated targets for the splicing activator tra2β in development.
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