For example, Lee et al reported a comprehensive HCC gene signature on a Chinese-Belgium dataset that overlapped our results in a highly significant manner (4.8 fold enrichment; Fisher Exact Test p-value = 1.4E-12 for the tumor tissue DFS signature, Table 1 and 2 ).
pmc-status-qastatus 0 pmc-status-live yes pmc-status-embargo no pmc-status-released yes pmc-prop-open-access yes pmc-prop-olf no pmc-prop-manuscript no pmc-prop-legally-suppressed no pmc-prop-has-pdf yes pmc-prop-has-supplement yes pmc-prop-pdf-only no pmc-prop-suppress-copyright no pmc-prop-is-real-version no pmc-prop-is-scanned-article no pmc-prop-preprint no pmc-prop-in-epmc yes pmc-license-ref CC BY Background Hepatocellular carcinoma (HCC) is the fifth most common cancer in the world, accounting for approximately one million deaths, with an increasing trend of new incidences annually [ 1 - 3 ].