It may be significant that, in VSMC, basal PEt formation in untreated cells accounts for half of the measured PLD activity [ 30 ], typical of a constitutive PLD2-like activity in these cells [ 32 ], whereas, in rat-1 fibroblasts, the presence of an inducible isoform is most probable.
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Protein kinase Czeta regulates phospholipase D activity in rat-1 fibroblasts expressing the alpha1A adrenergic receptor.
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