Rationale and design of the Leipzig (LIFE) Heart Study: phenotyping and cardiovascular characteristics of patients with coronary artery disease.

In contrast, patients with severe forms of CAD such as LMCAD had a stronger association with 9p21 than patients with obstructive CAD without LMCAD (OR 1.22, CI 1.01–1.48), even though it must be noted that these results were at the margin of statistical significance (p = 0.042; Figure 2 , Table 6 ).

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