Vitamin A supplementation in preschool children and risk of hearing loss as adolescents and young adults in rural Nepal: randomised trial cohort follow-up study.

Although originally planned for two years, the trial was stopped after 16 months for children aged 6 months or older after a data and safety monitoring analysis showed a highly significant 30% reduction in mortality attributed to vitamin A. 13 Thereafter, children aged 6 months or older received a high dose of vitamin A, whereas infants enrolled for a subsequent year remained in the trial up to 6 months of age.

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