Membrane-bound IL-21 promotes sustained ex vivo proliferation of human natural killer cells.

PLoS One · 2012 · PMC3261192 · PMID 22279576

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a nonsignificant trendno p-value reported

IL-2 or mbIL15-expanded NK cells showed a nonsignificant trend towards slightly longer mean telomere lengths during this first week, whereas mbIL21 caused a significant increase in the mean telomere lengths of expanded NK cells ( Figure 6A ) despite having the greatest amount of proliferation.

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