Absence of the DNA repair enzyme human 8-oxoguanine glycosylase is associated with an aggressive breast cancer phenotype.

Br J Cancer · 2012 · PMC3261678 · PMID 22108520

Europe PMC DOI

hedged sentences

0.0660

closest p · 1.3× alpha

0.0660

boldest claim

The sentences

a nonsignificant trendP =0.066so close (0.05 < p ≤ 0.1)

hOGG1-negative (irrespective of 8-oxodG status) breast cancer samples showed a nonsignificant trend to predict poor prognosis ( P =0.066).

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highly significantno p-value reported

Confirming studies are obviously required, but the observed difference is independent of other traditional prognostic factors and clinically highly significant.

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