Chronic stress and Alzheimer's disease-like pathogenesis in a rat model: prevention by nicotine.

Curr Neuropharmacol · 2011 · PMC3263455 · PMID 22654719

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highly significantno p-value reported

Most epidemiological studies have reported a highly significant negative correlation between cigarette smoking and AD [ 38 - 40 , 42 but see 42 , 43 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.