Disturbances of the hypothalamic-pituitary-adrenal axis and plasma electrolytes during experimental sepsis.

Ann Intensive Care · 2011 · PMC3264499 · PMID 22208725

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highly significantno p-value reported

Whereas negative control levels of ACTH ranged at 3 ng/ml, CLP induced a highly significant reduction of plasma ACTH levels between 6 hrs and 24 hrs after induction of sepsis, with a nadir 12 hrs after CLP surgery (~0.3 ng/ml).

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