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Reference programme: diagnosis and treatment of headache disorders and facial pain. Danish Headache Society, 2nd Edition, 2012.

J Headache Pain · 2012 · PMC3266527 · PMID 22270537

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an increasing trendno p-value reported
Consumption of medication follows an increasing trend and the recent introduction of novel specific migraine medications and novel prophylactic pharmaceuticals contributes to a considerable need to establish a systematic and updated treatment strategy in Denmark.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.