Identifying quantitative trait loci affecting resistance to congenital hypothyroidism in 129/SvJcl strain mice.

PLoS One · 2012 · PMC3267771 · PMID 22299049

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highly significantno p-value reported

We used the first principal component calculated from body weights at 5, 8 and 10 weeks as an indicator of CH, and QTL analysis mapped a major QTL showing a highly significant linkage to the distal portion of chromosome (Chr) 2; between D2Mit62 and D2Mit304 , particularly close to D2Mit255 .

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