Spreading convulsions, spreading depolarization and epileptogenesis in human cerebral cortex.

This difference was highly significant [72.3 (31.3–288.6) versus 7.4 (0.0–20.1) min per recording day, P = 0.007, n = 20, Mann–Whitney rank sum test].

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Relationship of spreading depolarizations with clinical and radiological parameters During Days 1–4 after aneurismal SAH, the peak depression period of the 24 h recording episodes showed a statistical trend towards a longer duration in patients with early structural brain damage [53.0 (18.4–377.9) versus 0.0 (0.0–129.0) min/24 h, P = 0.095, n = 24, Mann–Whitney rank sum test]; the difference in the peak number of spreading depolarizations was insignificant [8.0 (3.4–18.5) versus 0.0 (0.0–7.0) events per 24 h].

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