Many marker pairs showed highly significant interactions (Ayyadevara et al., 2003 ), lending support to the concept that longevity in natural populations depends on interactive networks of polymorphic genes (Leips and Mackay, 2002 ; Ayyadevara et al., 2003 ; Geiger-Thornsberry and Mackay, 2004 ).
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A narrow quantitative trait locus in C. elegans coordinately affects longevity, thermotolerance, and resistance to paraquat.
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