A novel approach for the simultaneous analysis of common and rare variants in complex traits.

Bioinform Biol Insights · 2012 · PMC3273305 · PMID 22346348

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highly significantno p-value reported

The δ j / δ̄ value (from Step III) for rare allele 3 was 4.205, which is much larger than the suggested highly significant critical value of γ = 2.5, indicating that rare allele 3 is strongly associated with obesity as measured by BMI.

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