highly significantP = 5.5 × 10 −7
However, the association between rs9465922 and IS remained highly significant after adjusting for self-reported diabetes status in our population (OR = 0.55, 95% = 0.44–0.70, P = 5.5 × 10 −7 ), suggesting the effect of this gene on IS may be independent of the effect of T2D.