Drug-induced cell cycle modulation leading to cell-cycle arrest, nuclear mis-segregation, or endoreplication.

BMC Cell Biol · 2011 · PMC3277280 · PMID 21226962

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possibly significantno p-value reported

Using cultured immortalized cells (HeLa and NMuMG cells) that constitutively express Fucci2, we identify several possibly significant variations in the cell cycle that cells exposed to anticancer drugs (inhibitors of DNA topoisomerase II or Cdk4) can undergo.

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