Barely Significant
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MicroRNA 146a (miR-146a) is over-expressed during prion disease and modulates the innate immune response and the microglial activation state.

PLoS One · 2012 · PMC3281888 · PMID 22363497

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The sentences

highly significantp<0.001actually significant
Highly significant (p<0.001) down-regulation of IL-6 and GM-CSF following miR-146a over-expression correlated well with our genomic data.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.