highly significantP < 0.001
Effect of aqueous and hydroalcoholic extracts of of Nigella sativa on infarct volume in MCAO rats TTC dye staining of brains of all extracts pretreated animals showed significant improvement in the infarct volume Aspirin, aqueous and hydroalcoholic extracts pretreated animals showed a highly significant reduction in infarct volume as compared with MCAO rats ( P < 0.001) [ Table 3 ].