Coexpression network analysis in abdominal and gluteal adipose tissue reveals regulatory genetic loci for metabolic syndrome and related phenotypes.

This module contained three of seven reported genes ( C3AR1 , HSD11B1 and CD68 ) with a highly significant MM (MM>0.75) from a previously identified macrophage-enriched metabolic network in subcutaneous adipose tissue in humans and mice that was associated with obesity-related traits and enriched for inflammatory response and macrophage activation pathway [11] ( Table S3 ).

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