Determinants of reactivity and selectivity in soluble epoxide hydrolase from quantum mechanics/molecular mechanics modeling.

Biochemistry · 2012 · PMC3290109 · PMID 22280021

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closest p

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may be significantno p-value reported

The ability of Tyr465 to form a hydrogen bond to the Asp333 Oδ2 atom (when His523 is neutral) may be significant for the proton shuttle step during hydrolysis.

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