Environmental and genetic factors in age related hearing impairment

BMC Geriatr · 2010 · PMC3290294

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highly significantno p-value reported

AHRI has been correlated with several single nucleotide polymorphisms (SNPs) in a region of KCNQ4; with a SNP in N-acetyltransferase 2 (confirming the role of oxidative stress in presbycusis); with a highly significant SNP in the GRHL2 gene; with a significant SNP at the GRM7 locus (indicating the possible effect of glutamate excitotoxicity in AHRI).

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