highly significantP < 0.01
Further stratification in quartiles of age showed that subjects in the 75th quartile (>55 years) had a much lower frequency of “at risk” FTO alleles (rs9939609 (A) = 0.42 and rs9930506 (G) = 0.44) compared to subjects in the 25th quartile (age > 35 years, 0.53 A allele and 0.54 G allele), a difference that was highly significant ( P < 0.01).