DNA damage in Nijmegen Breakage Syndrome cells leads to PARP hyperactivation and increased oxidative stress.

PLoS Genet · 2012 · PMC3291567 · PMID 22396666

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may be significantno p-value reported

In this respect, the role of nibrin in both DNA repair and cell cycle regulation may be significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.