Inherited variation in vitamin D genes is associated with predisposition to autoimmune disease type 1 diabetes.

Diabetes · 2011 · PMC3292339 · PMID 21441443

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a decreasing trendno p-value reported

Type 1 diabetes is a strongly inherited autoimmune disease that affects ~0.4% of European ancestry populations, and incidence has been increasing at 3% per year, with a decreasing trend in age at diagnosis since the 1950s ( 18 ).

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