Microglial p38α MAPK is critical for LPS-induced neuron degeneration, through a mechanism involving TNFα.

However, as shown in Figure 5C , when we quantified only the neurites that are smooth, indicative of a 'healthy' neurite, we found that LPS-stimulated WT microglia/neuron co-cultures showed a highly significant decrease in the healthy neurite arborization compared to the non-LPS-stimulated co-culture.

also in 132,142 other papers