The percent of neurons expressing Arc within the LPS-vehicle group showed an elevated trend, as compared to the aCSF-vehicle group, in all the areas analyzed that reached statistical significance in the CA3 area (40.59 ± 3.74 in LPS-vehicle vs. 28.95 ± 3.74% in aCSF-vehicle; p < 0.05).
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TNF-α protein synthesis inhibitor restores neuronal function and reverses cognitive deficits induced by chronic neuroinflammation.
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