Small-animal PET imaging of amyloid-beta plaques with [11C]PiB and its multi-modal validation in an APP/PS1 mouse model of Alzheimer's disease.

PLoS One · 2012 · PMC3302888 · PMID 22427802

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highly significantno p-value reported

The binding potential values for neocortex estimated by the same model for the whole study collective showed highly significant separation of all transgenic animals from controls and a clear distinction of AD animals belonging to different study groups ( Figure S10 ).

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