Most of the literature focuses little attention on the patient and surgical factors that influence third molar PEP.[ 7 ] However, one of the most important factors regulating oral health is saliva.[ 8 ] For diagnostic and prognostic purposes, routine dental practice should therefore include the measurement of certain important salivary factors such as pH and flow rate, which tend to have a highly significant linear correlation as well.
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Impacted lower third molars: Can preoperative salivary pH influence postoperative pain?
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Their study indicated that environmental stimuli regulated the activity of capsaicin-sensitive neurons innervating the dental pulp and these factors may be significant clinically in the development of dental pain.[ 11 ] Foodstuff, stress, surgery and drugs may influence salivary pH and a randomized clinical trial by Duane suggests that the use of high-dose xylitol chewing gum has beneficial effects on plaque pH and Streptococcus mutans in children at high risk for caries.[ 25 ] Many antibiotics are secreted in the saliva and may affect salivary pH (which may in turn affect PEP).[ 26 ] However, among these many contributing factors, very little, if any attention has been directed toward the relationship between salivary pH and the intensity of PEP.