Combining nitrous oxide with carbon dioxide decreases the time to loss of consciousness during euthanasia in mice--refinement of animal welfare?

PLoS One · 2012 · PMC3305278 · PMID 22438874

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might be significantno p-value reported

Although in all groups the acidaemia is likely to be mainly of respiratory origin, the lactic component might be significant for the mice euthanized with CO 2 and N 2 O or CO 2 and N 2 [61] .

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