Barely Significant
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An Alu element-associated hypermethylation variant of the POMC gene is associated with childhood obesity.

PLoS Genet · 2012 · PMC3305357 · PMID 22438814

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hedged sentence
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closest p · 0.0× alpha
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boldest claim

The sentences

highly significantp<0.001actually significant
We found the same methylation variant of CpG island 2 with a highly significant difference in the overall methylation score of position −4 to +6 in normal weight (23%) versus obese (32%) children (p<0.001) ( Figure 3D–3F ).

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