Barely Significant
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Sudden onset and blinding spontaneous direct carotid-cavernous fistula.

J Ophthalmic Vis Res · 2011 · PMC3306070 · PMID 22454707

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The sentences

may be significantno p-value reported
There may be significant periorbital or retro-ocular discomfort or pain, initially suggesting an inflammatory process or even the Tolosa–Hunt syndrome.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.