As shown in Table 7 , these comparisons revealed a highly significant risk associated with the S2/S3P, S3P and S1/S3D groups and, to a lesser extent, S1 and S3D as described in previous studies [ 21 , 40 ].
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HLA-DRB1 shared epitope genotyping using the revised classification and its association with circulating autoantibodies, acute phase reactants, cytokines and clinical indices of disease activity in a cohort of South African rheumatoid arthritis patients.
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