Prophylactic application of CpG oligonucleotides augments the early host response and confers protection in acute melioidosis.

PLoS One · 2012 · PMC3309019 · PMID 22448290

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highly significantno p-value reported

, measured the cytokine level in the animals prior to infection and found small but highly significant early increases in the level of IL-12p70 and IFN-γ, 24 h after CpG ODN injection [5] .

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