Epigenetic silencing of the circadian clock gene CRY1 is associated with an indolent clinical course in chronic lymphocytic leukemia.

PLoS One · 2012 · PMC3314606 · PMID 22470559

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highly significantno p-value reported

In all, there was a statistically highly significant inverse correlation between the percentage of methylated CpGs and CRY1 mRNA expression as detected by qRT-PCR ( Figure 2B and 3B ).

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