The allele-frequency spectrum in a decoupled Moran model with mutation, drift, and directional selection, assuming small mutation rates.

Theor Popul Biol · 2012 · PMC3315028 · PMID 22269092

Europe PMC DOI

hedged sentence

0.0000

closest p · 0.0× alpha

0.0000

boldest claim

The sentences

highly significantp < 2.2 × 1 0 − 16actually significant

The excess of GC to AT substitutions is highly significant, indicating non-equilibrium ( p < 2.2 × 1 0 − 16 ).

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