Changes of oscillatory activity in pitch processing network and related tinnitus relief induced by acoustic CR neuromodulation.

In a prospective, randomized, single blind, placebo-controlled proof of concept trial in 63 patients with chronic tonal tinnitus (“RESET study”) CR treatment turned out to be safe and well-tolerated and resulted in a highly significant decrease of tinnitus loudness and symptoms as measured by VAS and tinnitus questionnaire (TQ) scores ( Tass et al., 2012 ).

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