Barely Significant
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Pramipexole in restless legs syndrome: an evidence-based review of its effectiveness on clinical outcomes.

Core Evid · 2005 · PMC3321653 · PMID 22496675

1
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likely to be significantno p-value reported
However, given that 5–15% of the adult population is affected, the direct and indirect economic consequences of the disease are likely to be significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.