Barely Significant
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Global methylation patterns in idiopathic pulmonary fibrosis.

PLoS One · 2012 · PMC3323629 · PMID 22506007

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The sentences

highly significantp<10 −256actually significant
This overlap is highly significant, as the probability of such an overlap to occur in random is very low (p<10 −256 ). 45% of the 402 overlapped CpG islands are located in intronic and intergenic areas, 6% in promoters and 49% in exons.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.