borderline significantP = 0.105
When early response was added to these models the association with survival was not significant for DFS and only borderline significant for EFS (DFS: HR for early response corrected for age 1.75, 95% CI: 0.89–3.46, P = 0.105; EFS: HR for early response corrected for age and WBC count category 1.53, 95% CI: 0.98–2.39, P = 0.062), indicating that part of the association between early response and survival that was found in the univariate analyses could be explained through its association with other risk factors. 4.